MARLEX Engineering Inc.

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Automated Fluorescent Microscopy Based Analyser for Pathogen Detection

MARLEX has developed and successfully implemented fluorescent based microscopy imaging solutions. We have integrated laser illumination, narrow band filtering, and precision position control with our imaging system technology to capture exceptionally clear images at resolutions of 0.6 microns per pixel. We have developed custom software for the processing of images obtained from our imaging system designs and we have further integrated the software into a stand-alone DSP based product. Our design efforts have resulted in development of the BACscan™ reader.

Image of Laser Illumination 3D Profile of Laser Illumination Intensity Image of LED Illumination 3D Profile of LED Illumination Intensity Image Processing - Location of Centroids Analysis Results

Core Technologies Used in the Automated Fluorescent Microscopy Based Analyser for Pathogen Detection

  • Fluorescent based microscopy
  • Laser illumination
  • Optics (microscope lenses, narrow-band filters)
  • Precise 3-axis control of mechanical stage for positioning the BIOchip that contains the sample
  • Digital imaging and image processing
  • Algorithms for auto focus and analysis of sampled data
  • Touch-screen graphical user interface
  • Embedded controller
  • Custom embedded software for sample processing, data collection and data analysis

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